Must Know : Metabolism overview

  Carbohydrate Metabolism: • Digestion: Carbohydrates are broken down into simple sugars (e.g., glucose) during digestion. • Absorption:Gluc...

Sunday, 26 November 2023

Must Know : Metabolism overview

 


Carbohydrate Metabolism:


• Digestion: Carbohydrates are broken down into simple sugars (e.g., glucose) during digestion.

• Absorption:Glucose is absorbed into the bloodstream from the small intestine.

• Cellular Uptake:Cells take in glucose for energy or convert it into glycogen for storage.

• Glycolysis:Glucose is partially broken down in the cytoplasm, producing pyruvate and a small amount of ATP.

• Citric Acid Cycle (Krebs Cycle):Pyruvate is further broken down in the mitochondria, releasing more energy.

• Oxidative Phosphorylation: Electron transport chain generates the majority of ATP in the mitochondria.

• Glycogenesis and Glycogenolysis: Glycogen is formed from glucose when energy is abundant and broken down when energy is needed.

Protein Metabolism:

• Digestion: Proteins are broken down into amino acids during digestion.

• Absorption:Amino acids are absorbed into the bloodstream.

• Cellular Uptake: Cells use amino acids to build new proteins or for energy.

• Transamination: Amino acids undergo transamination to form different amino acids.

• Deamination: Removal of amino groups, leading to the formation of ammonia and keto acids.

• Gluconeogenesis: Some amino acids can be converted into glucose when needed.

Fat Metabolism:

• Digestion: Fats are broken down into fatty acids and glycerol during digestion.

• Absorption: Fatty acids are absorbed into the bloodstream.

• Cellular Uptake: Cells use fatty acids for energy or store them as triglycerides.

• Beta Oxidation: Fatty acids are broken down in the mitochondria to produce acetyl-CoA.

• Ketogenesis: Excess acetyl-CoA can be converted into ketone bodies during fasting or low-carbohydrate conditions.

• Lipogenesis: Formation of new fat molecules from acetyl-CoA, usually in response to an excess of glucose.

These processes are interconnected and regulated to maintain energy balance and support the diverse functions of the body.